SMBE 2016 Awards Announcement

Congratulations to the inaugural winners of the SMBE Junior Award for Independent Research, SMBE Margaret Dayhoff Award, SMBE Community Service Award and the SMBE Lifetime Contribution Award!

2016 SMBE Allan Wilson Award

Joanna Kelley


Dr. Joanna Kelley is an Assistant Professor in the School of Biological Sciences at Washington State University. She runs an evolutionary genomics laboratory that focuses on high-throughput genome sequencing and computational approaches to analyzing big data in genomics. Her research focuses on understanding the genomic basis for adaptation to extreme environments. She received her B.A. in mathematics and biology with honors from Brown University, working with Johanna Schmitt. She earned her Ph.D. in Genome Sciences from the University of Washington under Willie Swanson. As a postdoctoral researcher at the University of Chicago in Human Genetics with Molly Przeworski, she received a National Institutes of Health Ruth L. Kirschstein National Research Service Award. Dr. Kelley was also a postdoctoral researcher in the Department of Genetics at Stanford University with Carlos Bustamante.


2016 SMBE Margaret Dayhoff Award
Stephen I. Wright  

Stephen I. Wright is an Associate Professor and Canada Research Chair in Population Genomics at the University of Toronto. He completed an M.Sc. at McGill University with Dan Schoen and Thomas Bureau, his PhD with Deborah Charlesworth at the University of Edinburgh, and a postdoctoral fellowship with Brandon Gaut at the University of California Irvine.  His research interests focus on plant population and evolutionary genomics, with a particular interest in the genomic consequences of mating system evolution, quantification of genome-wide positive and negative selection, and the evolution of transposable elements.


2016 SMBE Community Service Award Winner
Bill Martin

As a scientist, Bill Martin has furthered our understanding of life's early history with contributions to the study of physiology, gene transfer and endosymbiosis in microbial evolution. He has served SMBE for well over a decade. As the Editor-in-Chief of
MBE 2003-2008, he fostered growth of the journal and the society while helping to usher SMBE into the age of electronic publishing. In 2009 he founded SMBE’s second journal, Genome Biology and Evolution, which was the first society-owned, open-access journal in the biological sciences.  He has served as the Editor-in-Chief of GBE since its inception, overseeing the journal’s contribution to the society and its benefit to the field. Bill is a fellow in the American Academy for Microbiology, a member of EMBO, and has been Chair of the Institute of Molecular Evolution at the University of Dusseldorf since 1999.  


2016 SMBE Motoo Kimura Lifetime Contribution Award Winner
Nancy Moran


Nancy Moran’s long-term interests are in the evolution of biological complexity, such as that apparent in complex life histories, in intimate interactions among species and in species-diversity of clades and communities. Her research has focused extensively on symbiosis, particularly between multicellular hosts and microbes.  In her storied career, she has demonstrated ancient coevolution between aphids and their plant hosts, and has characterized mutualistic symbiotic interactions between aphids and Buchnera bacteria and between other insect and symbiont clades. She found that these mutualisms are ancient, dating to the origins of major insect clades, and that the long term vertical transmission of the bacterial symbionts has caused extreme genome degradation and shrinkage. Her ongoing projects include phylogenetic and genomic studies of previously unstudied insect symbioses, experiments on gene expression of symbionts within hosts, computational reconstruction of the content and arrangement of genes in bacterial ancestors, and experimental investigations of coevolved gut communities within social bees. She has previously been awarded a MacArthur Fellowship and the International Prize for Biology, and has been a member of that National Academy of the Sciences since 2004.  She is currently the Leslie Surginer Endowed Professor in the Department of Integrative Biology at the University of Texas, Austin.  



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Abstract
The American Eel (Anguilla rostrata) has an exceptional life cycle characterized by panmictic reproduction at the species scale, random dispersal, and selection in a highly heterogeneous habitat extending from subtropical to subarctic latitudes. The genetic consequences of spatially-varying selection in this species have been investigated for decades, revealing subtle clines in allele frequency at a few loci that contrast with complete panmixia on the vast majority of the genome. Because reproduction homogenizes allele frequencies every generation, sampling size, and genomic coverage are critical to reach sufficient power to detect selected loci in this context. Here, we used a total of 710 individuals from 12 sites and 12,098 high-quality single nucleotide polymorphisms to re-evaluate the extent to which local selection affects the spatial distribution of genetic diversity in this species. We used environmental association methods to identify markers under spatially-varying selection, which indicated that selection affects ∼1.5% of the genome. We then evaluated the extent to which candidate markers collectively vary with environmental factors using additive polygenic scores. We found significant correlations between polygenic scores and latitude, longitude and temperature which are consistent with polygenic selection acting against maladapted genotypes in different habitats occupied by eels throughout their range of distribution. Gene functions associated with outlier markers were significantly enriched for the insulin signaling pathway, indicating that the trade-offs inherent to occupying such a large distribution range involve the regulation of metabolism. Overall, this study highlights the potential of the additive polygenic scores approach in detecting selective effects in a complex environment.

Unravelling the Genetic Diversity among Cassava Bemisia tabaci Whiteflies Using NextRAD Sequencing

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Abstract
Bemisia tabaci threatens production of cassava in Africa through vectoring viruses that cause cassava mosaic disease (CMD) and cassava brown streak disease (CBSD). B. tabaci sampled from cassava in eight countries in Africa were genotyped using NextRAD sequencing, and their phylogeny and population genetics were investigated using the resultant single nucleotide polymorphism (SNP) markers. SNP marker data and short sequences of mitochondrial DNA cytochrome oxidase I (mtCOI) obtained from the same insect were compared. Eight genetically distinct groups were identified based on mtCOI, whereas phylogenetic analysis using SNPs identified six major groups, which were further confirmed by PCA and multidimensional analyses. STRUCTURE analysis identified four ancestral B. tabaci populations that have contributed alleles to the six SNP-based groups. Significant gene flows were detected between several of the six SNP-based groups. Evidence of gene flow was strongest for SNP-based groups occurring in central Africa. Comparison of the mtCOI and SNP identities of sampled insects provided a strong indication that hybrid populations are emerging in parts of Africa recently affected by the severe CMD pandemic. This study reveals that mtCOI is not an effective marker at distinguishing cassava-colonizing B. tabaci haplogroups, and that more robust SNP-based multilocus markers should be developed. Significant gene flows between populations could lead to the emergence of haplogroups that might alter the dynamics of cassava virus spread and disease severity in Africa. Continuous monitoring of genetic compositions of whitefly populations should be an essential component in efforts to combat cassava viruses in Africa.

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Abstract
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